Dear OpenMS-Users, we are proud to announce the release of OpenMS 3.0. Grab it here In the following you find all important changes to the previous version: —————————————————————————————— New Tools: FLASHDeconv – Ultra-fast high-quality deconvolution enables online processing of top-down MS data (TOPP) FLASHDeconvWizard – A GUI assistant for FLASHDeconv execution. New Features: e.g. TMT18plex support (#6390) ProteinQuantifier supports iBAQ (#6107) OpenSwath: Add support for diaPASEF data with overlapping m/z and IM windows, and add new outputs on ion mobility features (delta_im), IM calibration (#5911, #6234, #6268) OpenSwathDecoyGenerator speed improvement and remove duplicates (#6054) NucleicAcidSearchEngine (NASE): user defined ribonucleotides with phosphorothioate linkages (#6337), JSON based ribonucleotides and updated to latest Modomics database (#6482) TargetedSpectraExtractor: more features (#6106) TOPPView: TheoreticalSpectrumGenerationDialog now supports generation of isotope patterns for metabolites (#6023); faster loading of external dragndrop data (#6837) colored commandline/console on all platforms (#6275) support for no cleavage for XTandemAdapter and CometAdapter (#6133). Percolator pin file reader (#6824) JSON export for OMS files(SQLite) (#6114) ParamEditor with more convenient StringList editing (#5135) load parameter values from a JSON formatted .json file. (Accessible via -ini. This will be helpful for Common Workflow Language users and others) FileFilter can remove convex hulls of features and consensusFeatures to reduce file size (#6140) Faster compile time (#6618) Improving code quality by fixing lots of linting warnings and leaks (e.g. #6839, #6831, #6829) Documentation: website redesign (visit openms.org) OpenMS user documentation is moved to openms.readthedocs.io/en/latest. OpenMS API reference and advanced developer documentation remains inside OpenMS doxygen documentation (https://abibuilder.cs.uni-tuebingen.de/archive/openms/Documentation/release/) pyopenms: pyopenms-extra is renamed to pyopenms-docs. Bug fixes e.g. GaussFilter when using ppm as width (#6830) NASE a-B ion masses (#6718), ID-Mapper for TMT data (#6758) FeatureFinderMetaboliteIdentification speed improvements (#6619) IDRipper speed improvements (#6584) Honor MissedCleavages in SimpleSearchEngine (#6889) TOPPView: fixed lots of display glitches, e.g. axis labels, goto dialog and easier re-use of components, etc (#6673, #6616, #6592, #6703, #6793) mzTab fixes for empty IDs (#6445) Fix GNPS error for empty scans in Bruker files (#6898) PrecursorPurity: handle unknown charge (#6283) OpenSwath: Fix duplicated transition error when multiple genes map to a single peptide (#5653) Fixed race condition when logging messages. Removed tools: InspectAdapter OMSSAAdapter MyriMatchAdapter CruxAdapter Supported compilers (when building from source): g++ (7.0 or later, tested up to v13.0) clang (?, tested up to v16) Visual Studio (2019(v16.8.4) or later) Full changelog: OpenMS 2.8 → 3.0 —————————————————————————————— Best regards, The OpenMS-Developers